Macroporous polymer supported azide and nanocopper (I): efficient and reusable reagent and catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from benzyl halides

نویسندگان

  • Mosadegh Keshavarz
  • Nasir Iravani
  • Abdolmohammad Ghaedi
  • Amanollah Zarei Ahmady
  • Masoumeh Vafaei-Nezhad
  • Sara Karimi
چکیده

Macroporous polymer supported nanoparticles of copper(I) iodide catalyst and macroporous polymer supported azide reagent were used to simplify the synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from various benzyl halides following the green chemistry principles. This new one-pot protocol facilitates the workup of the reaction and provides the products in short times and at high yields. Heterogeneous catalyst and reagent can be reloaded and reused at least for 5 runs without significant decrease in the yields.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2013